[3H]Ro 63-0563

Ligand id: 3246

Name: [3H]Ro 63-0563    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 117.52
Molecular weight 307.11
XLogP 1.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
5-HT6 receptor Hs Antagonist Antagonist 8.3 pKd - 1
pKd 8.3 (Kd 5x10-9 M) [1]