[3H]Ro 63-0563

Ligand id: 3246

Name: [3H]Ro 63-0563    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 117.52
Molecular weight 307.11
XLogP 1.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
5-HT6 receptor Hs Antagonist Antagonist 8.3 pKd - 1
pKd 8.3 (Kd 5x10-9 M) [1]