[Arg16]chicken secretin   

GtoPdb Ligand ID: 3293

Synonyms: [R16]chicken secretin
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
VPAC1 receptor Rn Agonist Agonist 9.0 pIC50 - 1
pIC50 9.0 (IC50 1x10-9 M) [1]
Description: Inhibition of [125I]VIP binding in membranes from CHO cells expressing recombinant receptor
secretin receptor Rn Agonist Agonist 7.7 pIC50 - 1
pIC50 7.7 (IC50 2x10-8 M) [1]
Description: Inhibition of [125I]Tyr25 secretin binding in membranes from CHO cells expressing recombinant receptor
VPAC1 receptor Hs Agonist Agonist 7.2 pIC50 - 1
pIC50 7.2 (IC50 6x10-8 M) [1]
Description: Inhibition of [125I]VIP binding in membranes from LoVo cells expressing recombinant receptor
VPAC2 receptor Hs Agonist Agonist 5.3 pIC50 - 1
pIC50 5.3 (IC50 5x10-6 M) [1]
Description: Inhibition of [125I]VIP binding in membranes from CHO cells expressing recombinant receptor
VPAC2 receptor Rn Agonist Agonist 5.0 pIC50 - 1
pIC50 5.0 (IC50 1x10-5 M) [1]
Description: Inhibition of [125I]VIP binding in membranes from CHO cells expressing recombinant receptor
PAC1 receptor Rn Agonist Agonist 4.7 pIC50 - 1
pIC50 4.7 (IC50 2x10-5 M) [1]
Description: Inhibition of [125I]-Ac-His1-PACAP-27 binding in membranes from CHO cells expressing recombinant receptor
PAC1 receptor Hs Agonist Full agonist - - -