Ligand id: 3480

Name: [3H]osanetant    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 10
Topological polar surface area 43.86
Molecular weight 605.26
XLogP 7.05
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
NK3 receptor Hs Antagonist Antagonist 9.9 pKd -
pKd 9.9 (Kd 1.3x10-10 M)