R-spondin-1   Click here for help

GtoPdb Ligand ID: 3697

Synonyms: hRspo1 | roof plate-specific spondin-1
Species: Human
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Natural/Endogenous Targets
Target
LGR4
LGR5
LGR6
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
LGR5 Ligand is endogenous in the given species Hs Agonist Full agonist 11.1 pEC50 - 1
pEC50 11.1 (EC50 8x10-12 M) [1]
LGR4 Ligand is endogenous in the given species Hs Agonist Full agonist 10.7 pEC50 - 1
pEC50 10.7 (EC50 2x10-11 M) [1]
LGR6 Ligand is endogenous in the given species Hs Agonist Full agonist - - - 1-2
[1-2]