Selectivity at ion channels
Key to terms and symbols		Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference nicotinic acetylcholine receptor α1 subunit Hs Antagonist Antagonist - - - ⤷ nicotinic acetylcholine receptor α7 subunit Hs Antagonist Antagonist - - - ⤷ (α7)5 nicotinic acetylcholine receptor α9 subunit Hs Antagonist Antagonist - - - ⤷ α9α10 (α9)5 nicotinic acetylcholine receptor α10 subunit Hs Antagonist Antagonist - - - ⤷ α9α10

Additional information and targets (data relate to human unless otherwise stated)
Description	Data	Reference
Commonly used antagonists at nicotinic acetylcholine receptor α8 subunit (avian)	(α8)5: α-bungarotoxin > atropine ≥ tubocurarine ≥ strychnine
Commonly used antagonists at nicotinic acetylcholine receptor α9 subunit	(α9)5: α-bungarotoxin > methyllycaconitine > strychnine ~ tropisetron > tubocurarine; α9α10: α-bungarotoxin > tropisetron = strychnine > tubocurarine
Commonly used antagonists at nicotinic acetylcholine receptor α10 subunit	α9α10: α-bungarotoxin > tropisetron = strychnine > tubocurarine
Commonly used antagonists at nicotinic acetylcholine receptor α1 subunit	(α1)2β1γδ and (α1)2β1δε: α-bungarotoxin > pancuronium > vecuronium > rocuronium > tubocurarine (IC50 = 43 - 82 nM)

Ligand mentioned in the following text fields
Nicotinic acetylcholine receptors (nACh) overview