[3H]AZ11637326

Ligand id: 3971

Name: [3H]AZ11637326    

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 25.36
Molecular weight 310.15
XLogP 3.77
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
nicotinic acetylcholine receptor α7 subunit Hs Agonist Full agonist 9.6 pKd - 1
pKd 9.6 (Kd 2.3x10-10 M) (α7)5 [1]