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Synonyms: Esmeron® | ORG-9426 | Zemuron®
rocuronium is an approved drug (FDA (2008))
Compound class: Synthetic organic
Comment: Approved as rocuronium bromide.
The neuromuscular blockade induced by rocuronium can be reversed by administering the selective relaxant binding agent (SRBA) sugammadex (PubChem CID 6918584, a.k.a. Bridion®, Org 25969).
|Due to the complex and varied nature of the precise subunit composition of nACh channels, and a paucity of affinity data with definitive molecular details, we have not tagged a primary target for this drug.|
|Additional information and targets (data relate to human unless otherwise stated)|
|Commonly used antagonists at nicotinic acetylcholine receptor α1 subunit||(α1)2β1γδ and (α1)2β1δε: α-bungarotoxin > pancuronium > vecuronium > rocuronium > tubocurarine (IC50 = 43 - 82 nM)|