5α-pregnan-3α-ol-20-one

Ligand id: 4108

Name: 5α-pregnan-3α-ol-20-one

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 37.3
Molecular weight 318.26
XLogP 6.1
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Natural/Endogenous Targets
Target
GABAA receptor α1 subunit
GABAA receptor α2 subunit
GABAA receptor α3 subunit
GABAA receptor α4 subunit
GABAA receptor α5 subunit
GABAA receptor α6 subunit
Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
GABAA receptor α1 subunit Hs Allosteric modulator Potentiation - - -
GABAA receptor α2 subunit Hs Allosteric modulator Potentiation - - -
GABAA receptor α3 subunit Hs Allosteric modulator Potentiation - - -
GABAA receptor α4 subunit Hs Allosteric modulator Potentiation - - -
GABAA receptor α5 subunit Hs Allosteric modulator Potentiation - - -
GABAA receptor α6 subunit Hs Allosteric modulator Potentiation - - -
Ligand mentioned in the following text fields