d-AP5   

GtoPdb Ligand ID: 4168

Synonyms: D-aminophosphonovaleric acid | D-AP-5
Compound class: Synthetic organic
Comment: The D-confirmation of AP5 is the more active isomer. This compoundis represented by ChEMBL without the charge (see link above).
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 133.49
Molecular weight 196.04
XLogP -4.06
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES OC(=O)C(CCCP(=O)(O)[O-])N
Isomeric SMILES OC(=O)[C@@H](CCCP(=O)(O)[O-])N
InChI InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-1/t4-/m1/s1
InChI Key VOROEQBFPPIACJ-SCSAIBSYSA-M
Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
GluN2A Hs Antagonist Antagonist - - -
[Binds to: glutamate site]
GluN2B Hs Antagonist Antagonist - - -
[Binds to: glutamate site]
GluN2C Hs Antagonist Antagonist - - -
[Binds to: glutamate site]
GluN2D Hs Antagonist Antagonist - - -
[Binds to: glutamate site]