formalin   Click here for help

GtoPdb Ligand ID: 4196

PDB Ligand
Compound class: Synthetic organic
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 17.07
Molecular weight 30.01
XLogP 0.02
No. Lipinski's rules broken 0
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Canonical SMILES C=O
Isomeric SMILES C=O
InChI InChI=1S/CH2O/c1-2/h1H2
Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
TRPA1 Mm Activator Activation 3.4 pEC50 - 1-2
pEC50 3.4 (EC50 3.981x10-4 M) covalent. This level of activity is also observed for rat TRPA1 [1-2]
Description: Calcium imaging
Conditions: HEK293 cells expressing human TRPA1 loaded with Fluo-4