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Synonyms: Amitiza® | SPI-0211
lubiprostone is an approved drug (FDA (2006))
Compound class: Synthetic organic
Comment: Chemically lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 (PGE1). It acts as selective activator of ClC-2 chloride channels located at the apical aspect of gastrointestinal epithelial cells.
View more information in the IUPHAR Pharmacology Education Project: lubiprostone