phencyclidine

Ligand id: 4282

Name: phencyclidine

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 2
Topological polar surface area 3.24
Molecular weight 243.2
XLogP 4.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
GluN2C Hs Channel blocker - 7.1 pIC50 - 1
pIC50 7.1 (IC50 7.7x10-8 M) [1]
Description: Measured vs. exogenously expressed zeta1/epsilon3 (GRIN1/GRIN2C) subunits, at pH 6.9
GluN2A Hs Channel blocker - - - -
GluN2B Hs Channel blocker - - - -
GluN2D Hs Channel blocker - - - -