FGF-1   Click here for help

GtoPdb Ligand ID: 4923

Synonyms: acidic fibroblast growth factor | beta-endothelial cell growth factor | heparin-binding growth factor 1 (HBGF-1)
Compound class: Endogenous peptide in human, mouse or rat
Comment: Monomer and homodimer
Species: Human
Additional information and targets (data relate to human unless otherwise stated)
Description Data Reference
Endogenous ligands at fibroblast growth factor receptor 2 FGF-1 (FGF1, P05230) > FGF-4 (FGF4, P08620), FGF-7 (FGF7, P21781), FGF-9 (FGF9, P31371) > FGF-2 (FGF2, P09038), FGF-6 (FGF6, P10767) 2
Endogenous ligands at fibroblast growth factor receptor 1 FGF-1 (FGF1, P05230), FGF-2 (FGF2, P09038), FGF-4 (FGF4, P08620) > FGF-5 (FGF5, P12034), FGF-6 (FGF6, P10767) 2
Endogenous ligands at fibroblast growth factor receptor 3 FGF-1 (FGF1, P05230), FGF-2 (FGF2, P09038), FGF-9 (FGF9, P31371) > FGF-4 (FGF4, P08620), FGF-8 (FGF8, P55075) 2
Endogenous ligands at fibroblast growth factor receptor 4 FGF-1 (FGF1, P05230), FGF-2 (FGF2, P09038), FGF-4 (FGF4, P08620), FGF-9 (FGF9, P31371) > FGF-6 (FGF6, P10767), FGF-8 (FGF8, P55075): FGF-19 (FGF19, O95750) 2
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
FP-1039 Peptide Hs None Binding 10.5 pKi - 1
⤷ pKi 10.5 (Ki 3x10-11 M) [1]
Description: Binding affinity determined by SPR analysis
Ligand mentioned in the following text fields
Fibroblast growth factor (FGF) family ligands comments