Ligand id: 5151

Name: bestatin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 4
Rotatable bonds 9
Topological polar surface area 112.65
Molecular weight 308.17
XLogP -0.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Leucine aminopeptidase 3 Bt Inhibitor Inhibition 9.2 pKi - 1,3
pKi 9.2 (Ki 6x10-10 M) [1,3]
Leukotriene A4 hydrolase Hs Inhibitor Inhibition 5.4 pKi - 2
pKi 5.4 (Ki 4x10-6 M) [2]
Description: Inhibition of LTB4 formation by isolated human enzyme in vitro.