Other ligands which bind to or alter the activity of this ligand
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Ligand Sp. Type Action Value Parameter Concentration range (M) Reference zansecimab Hs Antibody Binding 11.0 pKd - 3 ⤷ pKd 11.0 (Kd 1.1x10-11 M) [3] Description: Binding affinity to human Ang2 measured using proprietary Kinetic Exclusion Assay (Kinexa®) methodology. nesvacumab Hs Antibody Binding 10.7 pKd - 2 ⤷ pKd 10.7 (Kd 1.8x10-11 M) [2] vanucizumab Hs Antibody Binding 9.6 pKd - 1 ⤷ pKd 9.6 (Kd 2.4x10-10 M) [1] trebananib Hs Antibody Binding 9.2 pKd - 4 ⤷ pKd 9.2 (Kd 6.7x10-10 M) [4] faricimab Hs Antibody Binding 7.7 pKd - 5 ⤷ pKd 7.7 (Kd 2.2x10-8 M) [5] Description: Binding affinity to a ANG-2 RBD-Fc fusion protein bt ITC

Ligand mentioned in the following text fields
Type XII RTKs: TIE family of angiopoietin receptors overview