angiopoietin-2   Click here for help

GtoPdb Ligand ID: 5316

Synonyms: ANG-2
Species: Human
Other ligands which bind to or alter the activity of this ligand
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Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
zansecimab Peptide Primary target of this compound Hs Antibody Binding 11.0 pKd - 3
pKd 11.0 (Kd 1.1x10-11 M) [3]
Description: Binding affinity to human Ang2 measured using proprietary Kinetic Exclusion Assay (Kinexa®) methodology.
nesvacumab Peptide Primary target of this compound Hs Antibody Binding 10.7 pKd - 2
pKd 10.7 (Kd 1.8x10-11 M) [2]
vanucizumab Peptide Primary target of this compound Hs Antibody Binding 9.6 pKd - 1
pKd 9.6 (Kd 2.4x10-10 M) [1]
trebananib Peptide Primary target of this compound Hs Antibody Binding 9.2 pKd - 4
pKd 9.2 (Kd 6.7x10-10 M) [4]
faricimab Peptide Primary target of this compound Hs Antibody Binding 7.7 pKd - 5
pKd 7.7 (Kd 2.2x10-8 M) [5]
Description: Binding affinity to a ANG-2 RBD-Fc fusion protein bt ITC
Ligand mentioned in the following text fields