β-haemoglobin   

GtoPdb Ligand ID: 5370

Synonyms: hemoglobin beta chain | hemoglobin subunit beta
Comment: Beta globin (also referred to as HBB, β-globin, haemoglobin beta, hemoglobin beta, or preferably haemoglobin subunit beta) is a globin protein, which along with alpha globin (HBA), makes up the most common form of haemoglobin in adult humans, the haemoglobin A (HbA).
Species: Human
Bioactivity Comments
The approved drug voxelotor binds to sickle cell haemoglobin (HbS) and allosterically increases its affinity for oxygen, thus reducing HbS polymerisation and red blood cell sickling [1].
Ligand mentioned in the following text fields