Synonyms: GSK 1838705A | GSK1838705 | GSK1838705A
Compound class:
Synthetic organic
Comment: GSK-1838705A is an experimental inhibitor of the insulin receptor (INSR), insulin-like growth factor I receptor (IGF1R), and anaplastic lymphoma receptor tyrosine kinase (ALK) [2], with little inhibitory effect on other kinases.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Bioactivity Comments |
GSK-1838705A exhibits antitumour activity in vitro and in vivo [2]. |
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