IL-17F   Click here for help

GtoPdb Ligand ID: 5873

Synonyms: cytokine ML-1 | Interleukin-17F
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: Forms homodimeric ligand IL-17F and heterodimer IL-17A/IL-17F with IL-17A.
Species: Human
Natural/Endogenous Targets
Target
Interleukin-17 receptor
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-17 receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -
⤷
Other ligands which bind to or alter the activity of this ligand
Key to terms and symbols Click column headers to sort
Ligand Sp. Type Action Value Parameter Concentration range (M) Reference
sonelokimab Peptide Primary target of this compound Hs Antibody Binding 11.9 pKd - 2
⤷ pKd 11.9 (Kd 1.14x10-12 M) [2]
bimekizumab Peptide Approved drug Primary target of this compound Hs Antibody Binding - - - 1
⤷ [1]