IL-36γ   Click here for help

GtoPdb Ligand ID: 5883

Synonyms: IL-1-related protein 2 (IL-1RP2) | interleukin-1 epsilon (IL-1E) | interleukin-1 family member 9 | interleukin-36 gamma
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: IL-36γ is a proinflammatory cytokine.
Species: Human
Natural/Endogenous Targets
Target
Interleukin-36 receptor
Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-36 receptor Ligand is endogenous in the given species Hs Agonist Agonist - - -
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Targets where the ligand is described in the comment field
Target Comment
Interleukin-36 receptor IL-36 receptor antagonist (IL36RN, Q9UBH0) is a highly specific antagonist of the response to IL-36γ (IL36G, Q9NZH8).