indirubin derivative E804

Ligand id: 5988

Name: indirubin derivative E804

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 7
Topological polar surface area 106.94
Molecular weight 365.14
XLogP 2.96
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
eukaryotic translation initiation factor 2 alpha kinase 2 Hs Inhibitor Inhibition >7.0 pIC50 - 2
pIC50 >7.0 (IC50 <1x10-7 M) [2]