View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Natural/Endogenous Targets
Target BB1 receptor BB2 receptor

Selectivity at GPCRs
Key to terms and symbols		Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference BB2 receptor Hs Agonist Full agonist 9.7 – 9.8 pIC50 - 1 ⤷ pIC50 9.7 – 9.8 (IC50 1.9x10-10 – 1.7x10-10 M) [1] BB1 receptor Hs Agonist Full agonist 6.8 – 6.9 pIC50 - 1 ⤷ pIC50 6.8 – 6.9 (IC50 1.48x10-7 – 1.23x10-7 M) [1] BB1 receptor Rn Agonist Full agonist 6.6 pIC50 - 1 ⤷ pIC50 6.6 (IC50 2.3x10-7 M) [1]