MM54   Click here for help

GtoPdb Ligand ID: 6186

Synonyms: cyclo(1-6)CRPRLC-KH-cyclo(9-14)CRPRLC
Comment: MM54 is an apelin receptor antagonist. It has been to suppress tumour growth and increase survival in an intracranial xenograft mouse model of glioblastoma [1].
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
apelin receptor Hs Antagonist Antagonist 8.2 pKi - 2
pKi 8.2 (Ki 7.1x10-9 M) [2]