Ligand id: 6333


Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 19
Hydrogen bond donors 7
Rotatable bonds 11
Topological polar surface area 317.21
Molecular weight 601.08
XLogP -5.29
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
TRPM2 Hs Activator Activation 4.0 pKd - 1
pKd 4.0 (Kd 1x10-4 M) [1]
Voltage: -100.0 mV