Synonyms: CCG 1423 | CCG1423
Compound class:
Synthetic organic
Comment: CCG-1423 inhibits RhoA transcriptional signaling via an unknown mechanism of action but is tool compound for the disruption of transcriptional responses of the Rho pathway in cancer.
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Bioactivity Comments |
CCG-1423 inhibits Rho-dependent invasion by PC-3 prostate cancer cells. It acts downstream of Rho and shows specificity for SRE.L-mediated transcription [1]. |