certolizumab pegol

Ligand id: 6774

Name: certolizumab pegol

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Bioactivity Comments
Certolizumab pegol neutralises soluble TNFα in vitro, with an IC90 of 3ng/ml [2], neutralises the effects mediated by membrane bound TNFα, and inhibits production of IL-1β in monocytes stimulated with LPS.
Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
tumour necrosis factor shed form Hs Antibody Binding - - - 2
Description: Note IC90 value of 3ng/ml is provided