golimumab   

GtoPdb Ligand ID: 6776

Synonyms: CNTO-148 | CNTO148 | Simponi®
golimumab is an approved drug (FDA (2009), EMA (2009))
Compound class: Antibody
Comment: TNFα inhibitor.
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Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
tumour necrosis factor shed form Hs Antibody Binding 10.7 pIC50 - 2
pIC50 10.7 (IC50 1.8x10-11 M) [2]
Description: Affinity for soluble TNFα measured by surface plasmon resonance