golimumab

Synonyms: CNTO-148 | CNTO148 | Simponi®

golimumab is an approved drug (FDA (2009), EMA (2009))

Compound class: Antibody

Comment: TNFα inhibitor.

View more information in the IUPHAR Pharmacology Education Project: golimumab

Selectivity at ligand targets

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Target			Sp.	Type	Action	Value	Parameter	Concentration range (M)	Reference
tumour necrosis factor shed form			Hs	Antibody	Binding	10.7	pIC₅₀	-	2
⤷	pIC₅₀ 10.7 (IC₅₀ 1.8x10^-11 M) [2] Description: Affinity for soluble TNFα measured by surface plasmon resonance