Summary of Clinical Use

Used in adults with various inflammatory conditions [3] e.g. moderate to severe active rheumatoid arthritis [1], active psoriatic arthritis, active ankylosing spondylitis and moderate to severe ulcerative colitis.

Mechanism Of Action and Pharmacodynamic Effects

Anti-TNFα monoclonal antibody which binds and neutralises soluble and membrane human TNFα, a pro-inflammatory cytokine associated with chronic inflammation.

External links

For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com European Medicines Agency (EMA)