basiliximab   Click here for help

GtoPdb Ligand ID: 6879

Synonyms: CHI-621 | L04AC02 | SDZ-CHI-621 | Simulect®
Approved drug Immunopharmacology Ligand
basiliximab is an approved drug (FDA (1998), EMA (1998))
Compound class: Antibody
Comment: Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
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View more information in the IUPHAR Pharmacology Education Project: basiliximab

Bioactivity Comments
Peptide sequence analysis reveals that patent US6383487 [1] covers the design and uses of basiliximab. However, this patent does not provide affinity data for the interaction between the antibody and its target, IL-2, and we have been unable to find accessible data elsewhere.
Selectivity at catalytic receptors
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Interleukin-2 receptor subunit α Hs Antibody Binding - - -