panitumumab   Click here for help

GtoPdb Ligand ID: 6883

Synonyms: ABX-EGF | ABX-EGF Mab | Vectibix®
Approved drug
panitumumab is an approved drug (FDA (2006), EMA (2007))
Compound class: Antibody
Comment: Binds to and competitively inhibits the activity of the epidermal growth factor receptor.
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Selectivity at catalytic receptors
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
epidermal growth factor receptor Primary target of this compound Hs Antibody Antagonist 10.3 pKd - 1
pKd 10.3 (Kd 5x10-11 M) [1]