panitumumab   Click here for help

GtoPdb Ligand ID: 6883

Synonyms: ABX-EGF | ABX-EGF Mab | Vectibix®
Approved drug
panitumumab is an approved drug (FDA (2006), EMA (2007))
Compound class: Antibody
Comment: Binds to and competitively inhibits the activity of the epidermal growth factor receptor.
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1. Foon KA, Yang XD, Weiner LM, Belldegrun AS, Figlin RA, Crawford J, Rowinsky EK, Dutcher JP, Vogelzang NJ, Gollub J et al.. (2004)
Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody.
Int J Radiat Oncol Biol Phys, 58 (3): 984-90. [PMID:14967460]