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Synonyms: amlodipine besylate | amlodipine maleate | Copalia® (amlodipine + valsartan) | Katerzia® (amlodipine oral suspension, 1 mg/mL) | Norvasc® | UK-4834011
amlodipine is an approved drug (FDA (1992), EMA (2007))
Compound class: Synthetic organic
Comment: Amlodipine is a long-acting dihydropyridine class calcium channel blocker.
Amlodipine is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: amlodipine
|Due to the complex nature of this drug's MMOA, and the paucity of (human) affinity data, we do not tag a primary drug target.
Amlodipine has been described as a gating modifier of Cav channels .
|Selectivity at ion channels|
|Key to terms and symbols||Click column headers to sort|