Synonyms: Stablon® | tianeptine sodium
tianeptine is an approved drug
Compound class:
Synthetic organic
Comment: Chemically tianeptine can be classified as a tricyclic antidepressant (TCA), but evidence suggests that it has a quite different pharmacological mechanism of action compared to typical TCAs [2-4].
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Bioactivity Comments |
In electrophysiology experiments using mouse hippocampal slices, 100 μM tianeptine increases the amplitude of isolated AMPA receptor mediated fEPSPs (field excitatory post-synaptic potentials) by approximately 163% after 60 min administration [6]. As there appears to be no publicly available bioactivity data for this drug at its human molecular target(s) we have not mapped a primary drug target in this instance. |