EFPPEA   

GtoPdb Ligand ID: 7774

Synonyms: ethyl-furo-pyrazolo-pyridine-ethyl-acetamide | N-[2-(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethyl]acetamide
Compound class: Synthetic organic
2D Structure
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Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 55.63
Molecular weight 273.15
XLogP 1.29
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES CCc1nn2c(c1CCNC(=O)C)c1CCOc1cc2
Isomeric SMILES CCc1nn2c(c1CCNC(=O)C)c1CCOc1cc2
InChI InChI=1S/C15H19N3O2/c1-3-13-11(4-7-16-10(2)19)15-12-6-9-20-14(12)5-8-18(15)17-13/h5,8H,3-4,6-7,9H2,1-2H3,(H,16,19)
InChI Key IZDHETWMKYCGAU-UHFFFAOYSA-N
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
MT1 receptor Hs Agonist Full agonist 10.2 pKi - 1
pKi 10.2 (Ki 6.2x10-11 M) [1]
MT2 receptor Hs Agonist Full agonist 9.4 pKi - 1
pKi 9.4 [1]