EFPPEA   Click here for help

GtoPdb Ligand ID: 7774

Synonyms: ethyl-furo-pyrazolo-pyridine-ethyl-acetamide | N-[2-(2-Ethyl-8,9-dihydrofuro[3,2-c]pyrazolo[1,5-a]pyridin-1-yl)ethyl]acetamide
Compound class: Synthetic organic
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 55.63
Molecular weight 273.15
XLogP 1.29
No. Lipinski's rules broken 0
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Canonical SMILES CCc1nn2c(c1CCNC(=O)C)c1CCOc1cc2
Isomeric SMILES CCc1nn2c(c1CCNC(=O)C)c1CCOc1cc2
InChI InChI=1S/C15H19N3O2/c1-3-13-11(4-7-16-10(2)19)15-12-6-9-20-14(12)5-8-18(15)17-13/h5,8H,3-4,6-7,9H2,1-2H3,(H,16,19)
Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
MT1 receptor Hs Agonist Full agonist 10.2 pKi - 1
pKi 10.2 (Ki 6.2x10-11 M) [1]
MT2 receptor Hs Agonist Full agonist 9.4 pKi - 1
pKi 9.4 [1]