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Synonyms: AZD 9056 | AZD-9056
Compound class: Synthetic organic
Comment: AZD9056 is a potent, selective, orally bioavailable P2X7 receptor antagonist.
This compound was in the AstraZeneca/NCATS repurposing list from 2012.
|The NIH National Center for Advancing Translational Sciences (NCATS) record for AZD9056 provides bioactivity data as follows: The IC50 for AZD9056-induced inhibition of pro-inflammatory IL-1β and IL-18 release from human peripheral monocytes is 10-13nM.|