Synonyms: BDP 37 | CX 614 | CX-614
Compound class:
Synthetic organic
Comment: CX614 is a positive allosteric modulator of the AMPA receptor [1] with respect to AMPA.
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Bioactivity Comments |
CX614 at 2.3μM doubles the current flow in cultured rat embryonic hippocampal neurons in a patch clamp electrophysiology assay, indicating positive modulation AMPA-induced AMPA receptor activity [1]. |