Ligand id: 7842

Name: CX614

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Topological polar surface area 48
Molecular weight 247.08
XLogP 1.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
CX614 at 2.3μM doubles the current flow in cultured rat embryonic hippocampal neurons in a patch clamp electrophysiology assay, indicating positive modulation AMPA-induced AMPA receptor activity [1].