Synonyms: compound 14 [PMID: 24900381]
Compound class:
Synthetic organic
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Bioactivity Comments |
USP7 and USP47 inhibitors are considered to have potential as cancer therapeutics via their ability to stabilize the tumor suppressor p53 and to decrease DNA polymerase β both of which are potential anticancer effects. This compound inhibits USP7 with an IC50 of 420nM, and USP47 with and IC50 of 1000nM [1]. |