Ligand id: 8230

Name: IOX1

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 70.42
Molecular weight 189.04
XLogP 1.33
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
lysine demethylase 3A Hs Inhibitor Inhibition 7.0 pIC50 - 1
pIC50 7.0 (IC50 1x10-7 M) [1]
lysine demethylase 4C Hs Inhibitor Inhibition 6.2 pIC50 - 1
pIC50 6.2 (IC50 6x10-7 M) [1]
lysine demethylase 6B Hs Inhibitor Inhibition 5.8 pIC50 - 1
pIC50 5.8 (IC50 1.6x10-6 M) [1]
egl-9 family hypoxia inducible factor 1 Hs Inhibitor Inhibition 4.5 pIC50 - 1
pIC50 4.5 (IC50 3.3x10-5 M) [1]