abagovomab   Click here for help

GtoPdb Ligand ID: 8265

Synonyms: ACA125 | MEN-2234
Compound class: Antibody
Comment: Abagovomab is an anti-idiotype monoclonal antibody. The antibody is designed to functionally mimic the epithelial ovarian cancer antigen CA-125 (aka mucin 16: MUC16, Q8WXI7) [1,3,5].
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.
Bioactivity Comments
As an anti-idiotypic antibody this agent does not have a primary molecular target. However, the primary target of the immune response elicited by abagovomab is the tumour antigen CA-125 (a.k.a. MUC16) as described in patent US20090104184 [3].