Synonyms: ChemBridge ID 9033823 [1]
Compound class:
Synthetic organic
Comment: cmp5 is reported as a novel, first-in-class, selective small molecule inhibitor of PRMT5 [1], an arginine methyltransferase (RMT) of the histone methyltransferase (HMT) family.
|
|
Bioactivity Comments |
Inhibition of PRMT5 by cmp5 is reported to restore regulatory checkpoints in lymphoma cells, thereby repressing B lymphocyte transformation [1]. |
Selectivity at enzymes | ||||||||||||||||||||||||||||||||||
Key to terms and symbols | Click column headers to sort | |||||||||||||||||||||||||||||||||
|