A(4-24)(B7-24)H2   Click here for help

GtoPdb Ligand ID: 8346

Synonyms: A(4-24)(B7-24)H2 relaxin
Comment: Synthetic analogue of human relaxin. A heterodimer consisting of two chains, each a truncated from of one of the subunit chains of the natural sequence of human relaxin.
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Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP1 Hs Agonist Full agonist 7.0 pKd - 1
pKd 7.0 [1]
RXFP2 Hs Antagonist Antagonist 6.0 pKi - 1
pKi 6.0 [1]
RXFP1 Hs Agonist Full agonist 8.2 pEC50 - 1
pEC50 8.2 [1]
RXFP2 Hs Antagonist Antagonist 6.0 pEC50 - 1
pEC50 6.0 [1]