SDF-1, 1-9[P2G] dimer   Click here for help

GtoPdb Ligand ID: 851

Synonyms: stromal cell-derived factor-1, N-terminal fragment analogue dimer
Comment: Dimeric ligand with identical subunits consisting of the first 9 amino acids of SDF-1 (common to the α and β chains). Proline residue 2 of the natural sequence is replaced by glycine. The structure of each subunit is shown under the structure tab
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CXCR4 Hs Antagonist Antagonist 5.6 pKi - 1
pKi 5.6 [1]