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Synonyms: stromal cell-derived factor-1, N-terminal fragment analogue dimer
Compound class:
Peptide or derivative
Comment: Dimeric ligand with identical subunits consisting of the first 9 amino acids of SDF-1 (common to the α and β chains). Proline residue 2 of the natural sequence is replaced by glycine. The structure of each subunit is shown under the structure tab
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Loetscher P, Gong JH, Dewald B, Baggiolini M, Clark-Lewis I. (1998)
N-terminal peptides of stromal cell-derived factor-1 with CXC chemokine receptor 4 agonist and antagonist activities. J Biol Chem, 273 (35): 22279-83. [PMID:9712844] |
