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Synonyms: Bavencio® | MSB-0010718C | MSB0010718C
avelumab is an approved drug (EMA & FDA (2017))
Compound class: Antibody
Comment: Avelumab is a programmed death-ligand 1 (PD-L1; CD274) blocking human IgG1 lambda monoclonal antibody . It is the first drug approved for the treatment of Merkel cell carcinoma (MCC).
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.
|A patent search identifies that peptide sequences of the heavy and light chains of avelumab are identical to SEQ ID NO: 24 and SEQ ID NO: 25 (respectively) in WO2013079174 A1 . The data in the table below is that proovided for clone A09-246-2, a preferred embodiment of the patent.|
|Selectivity at ligand targets|
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