avelumab   Click here for help

GtoPdb Ligand ID: 8735

Synonyms: Bavencio® | MSB-0010718C | MSB0010718C
Approved drug Immunopharmacology Ligand
avelumab is an approved drug (EMA & FDA (2017))
Compound class: Antibody
Comment: Avelumab is a programmed death-ligand 1 (PD-L1; CD274) blocking human IgG1 lambda monoclonal antibody . It is the first drug approved for the treatment of Merkel cell carcinoma (MCC).
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.
Immunopharmacology Comments
Avelumab is included in GtoImmuPdb as it is an immune checkpoint inhibitor, a mechanism of action now widely accepted as efficacious for cancer immunotherapy [2-3].