GtoPdb Ligand ID: 8964

Synonyms: AMG-403 | JNJ-42160443
Compound class: Antibody
Comment: Fulranumab was an investigational, fully human IgG2κ monoclonal antibody targeting nerve growth factor (NGF) [1,6].
Peptide sequence information for this antibody is available from its IMGT/mAb-DB record.
BLAST peptide sequence analysis reveals identical matches to peptide sequences submitted with patent US7601818 [9], which belong to antibody clone 4D4 therein.
Selectivity at ligand targets
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
NGF Hs Antibody Binding 11.4 pKd - 9
pKd 11.4 (Kd 4x10-12 M) [9]