JNJ-42165279

Ligand id: 9012

Name: JNJ-42165279

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 66.93
Molecular weight 410.1
XLogP 1.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
Fatty acid amide hydrolase Hs Inhibitor Inhibition 7.1 pIC50 - 3
pIC50 7.1 (IC50 7.5x10-8 M) [3]
Fatty acid amide hydrolase Rn Inhibitor Inhibition 6.5 pIC50 - 3
pIC50 6.5 (IC50 3.2x10-7 M) [3]