JNJ-42165279

Ligand id: 9012

Name: JNJ-42165279

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 66.93
Molecular weight 410.1
XLogP 1.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Fatty acid amide hydrolase Hs Inhibitor Inhibition 7.1 pIC50 - 3
pIC50 7.1 (IC50 7.5x10-8 M) [3]
Fatty acid amide hydrolase Rn Inhibitor Inhibition 6.5 pIC50 - 3
pIC50 6.5 (IC50 3.2x10-7 M) [3]