urocortin 2   

GtoPdb Ligand ID: 921

Synonyms: urocortin II
Species: Human
Natural/Endogenous Targets
Target
CRF1 receptor
CRF2 receptor
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CRF2 receptor Mm Agonist Full agonist 9.3 pKd - 2-3
pKd 9.3 [2-3]
CRF2 receptor Rn Agonist Full agonist 8.8 pKd - 2
pKd 8.8 [2]
CRF2 receptor Hs Agonist Full agonist 8.5 – 8.6 pKd - 1
pKd 8.5 – 8.6 [1]
CRF1 receptor Hs Agonist Full agonist 5.3 – 5.4 pKd - 1
pKd 5.3 – 5.4 [1]
Ligand mentioned in the following text fields