Synonyms: ABT-555 | AE12-1Y-QL
Compound class:
Antibody
Comment: Elezanumab (ABT-555) is a fully human monoclonal antibody targeting repulsive guidance molecule-a (RGMA), in development as a potential therapy for multiple sclerosis (MS).
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record. BLAST peptide anaylsis reveals identical matches with peptides claimed in patent WO2013112922 [2]. |
Bioactivity Comments |
Functional and preclinical data for antibody AE12-1Y-QL are presented in patent WO2013112922 [2], although no affinity value is provided for antibody-RGMA binding. |
Selectivity at other protein targets | ||||||||||||||||||||||||||||||||||
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