GSK429286A

Ligand id: 9356

Name: GSK429286A

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 86.88
Molecular weight 432.12
XLogP 3.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
Rho associated coiled-coil containing protein kinase 1 Hs Inhibitor Inhibition 7.8 pIC50 - 1
pIC50 7.8 (IC50 1.4x10-8 M) [1]
ribosomal protein S6 kinase A1 Hs Inhibitor Inhibition 6.1 pIC50 - 1
pIC50 6.1 (IC50 7.8x10-7 M) [1]