GtoPdb Ligand ID: 9421

Synonyms: Alzumab® | T1h
itolizumab is an approved drug (DCGI (India; 2013))
Compound class: Antibody
Comment: Itolizumab is a first in class humanized IgG1 monoclonal antibody targeting T cell CD6. It is being developed by Biocon Limited for its anti-inflammatory potential in autoimmune conditions.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD6 Hs Antibody Binding 7.2 pKi - 1
pKi 7.2 (Ki 6x10-8 M) [1]